Keeping your Twitter account clean and professional means rising above the critics who have nothing of substance to criticize you about.
This is some of the best advice I’ve ever heard, not just with regard to Twitter, but with regard to social networking and social management in general.
It’s hard sometimes to not get baited by the trolls, or just disagreeable members of a community. But the good moderators and community managers know when to pause, take a breath and just wait for the annoying yammering of one, or some, to die down.
I try, as often as possible, to stop before I respond to any comment and answer: What is the benefit of responding? If there is none, I don’t answer.